Version 5.4
Bos taurus Protein: F8
Summary
InnateDB Protein IDBP-683717.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol F8
Protein Name coagulation factor VIII, procoagulant component
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000036581
InnateDB Gene IDBG-632125 (F8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0007155 cell adhesion
GO:0030168 platelet activation
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
IPR008972 Cupredoxin
IPR008979 Galactose-binding domain-like
IPR011706 Multicopper oxidase, type 2
IPR011707 Multicopper oxidase, type 3
PFAM PF00754
PF07731
PF07732
PRINTS
PIRSF
SMART SM00231
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E5W1
UniProt Splice Variant
Entrez Gene 100271720
UniGene Bt.1262
RefSeq NP_001138980
HUGO HGNC:3546
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02070026 DAAA02070027 DAAA02070028
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca