InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BIRC6

Summary

InnateDB Protein

IDBP-683730.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BIRC6

Protein Name

baculoviral IAP repeat containing 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053672

InnateDB Gene

IDBG-632006 (BIRC6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0004869	cysteine-type endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0001890	placenta development
GO:0006464	cellular protein modification process
GO:0006915	apoptotic process
GO:0008152	metabolic process
GO:0008284	positive regulation of cell proliferation
GO:0015031	protein transport
GO:0016567	protein ubiquitination
GO:0032465	regulation of cytokinesis
GO:0042127	regulation of cell proliferation
GO:0043066	negative regulation of apoptotic process
GO:0060711	labyrinthine layer development
GO:0060712	spongiotrophoblast layer development
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0000922	spindle pole
GO:0005768	endosome
GO:0005802	trans-Golgi network
GO:0005815	microtubule organizing center
GO:0016020	membrane
GO:0030496	midbody

Protein Structure and Domains

PDB ID

InterPro

IPR000608 Ubiquitin-conjugating enzyme, E2
IPR001370 Baculoviral inhibition of apoptosis protein repeat
IPR008883 Ubiquitin E2 variant, N-terminal
IPR008979 Galactose-binding domain-like
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR017986 WD40-repeat-containing domain
IPR022103 Baculoviral IAP repeat-containing protein 6

PFAM

PF00179
PF00653
PF05743
PF12356

PRINTS

PIRSF

SMART

SM00238

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite