InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PHF12

Summary

InnateDB Protein

IDBP-683764.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHF12

Protein Name

PHD finger protein 12

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021255

InnateDB Gene

IDBG-632159 (PHF12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001106	RNA polymerase II transcription corepressor activity
GO:0001222	transcription corepressor binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0035091	phosphatidylinositol binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-templated

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0016580	Sin3 complex
GO:0017053	transcriptional repressor complex

Protein Structure and Domains

PDB ID

InterPro

IPR000253 Forkhead-associated (FHA) domain
IPR001965 Zinc finger, PHD-type
IPR008984 SMAD/FHA domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00498
PF00628

PRINTS

PIRSF

SMART

SM00240
SM00249

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite