Version 5.4
Bos taurus Protein: OSTF1
Summary
InnateDB Protein IDBP-684033.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSTF1
Protein Name Osteoclast-stimulating factor 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003560
InnateDB Gene IDBG-632428 (OSTF1)
Protein Structure
UniProt Annotation
Function Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR002110 Ankyrin repeat
IPR011511 Variant SH3 domain
IPR020683 Ankyrin repeat-containing domain
PFAM PF00018
PF14604
PF00023
PF13606
PF07653
PF11929
PF12796
PRINTS PR00452
PR01415
PIRSF
SMART SM00326
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8MJ50
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281961
UniGene
RefSeq NP_776834
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF523267 BC112669
GenPept AAI12670 AAM82160

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca