Bos taurus Protein: MECP2
Summary
InnateDB Protein IDBP-684236.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MECP2
Protein Name methyl CpG binding protein 2 (Rett syndrome)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000056184
InnateDB Gene IDBG-632607 (MECP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008327 methyl-CpG binding
GO:0010385 double-stranded methylated DNA binding
GO:0019904 protein domain specific binding
GO:0035197 siRNA binding
GO:0044822 poly(A) RNA binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0001662 behavioral fear response
GO:0001666 response to hypoxia
GO:0001964 startle response
GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure
GO:0002087 regulation of respiratory gaseous exchange by neurological system process
GO:0006020 inositol metabolic process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006342 chromatin silencing
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006355 regulation of transcription, DNA-templated
GO:0006541 glutamine metabolic process
GO:0006576 cellular biogenic amine metabolic process
GO:0007268 synaptic transmission
GO:0007416 synapse assembly
GO:0007420 brain development
GO:0007585 respiratory gaseous exchange
GO:0007612 learning
GO:0007613 memory
GO:0007616 long-term memory
GO:0008104 protein localization
GO:0008211 glucocorticoid metabolic process
GO:0008284 positive regulation of cell proliferation
GO:0008344 adult locomotory behavior
GO:0008542 visual learning
GO:0009405 pathogenesis
GO:0009791 post-embryonic development
GO:0010468 regulation of gene expression
GO:0016358 dendrite development
GO:0016571 histone methylation
GO:0016573 histone acetylation
GO:0019230 proprioception
GO:0019233 sensory perception of pain
GO:0021549 cerebellum development
GO:0021591 ventricular system development
GO:0030182 neuron differentiation
GO:0031061 negative regulation of histone methylation
GO:0031175 neuron projection development
GO:0032048 cardiolipin metabolic process
GO:0033555 multicellular organismal response to stress
GO:0035067 negative regulation of histone acetylation
GO:0035176 social behavior
GO:0040029 regulation of gene expression, epigenetic
GO:0042551 neuron maturation
GO:0043524 negative regulation of neuron apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046470 phosphatidylcholine metabolic process
GO:0048167 regulation of synaptic plasticity
GO:0050432 catecholamine secretion
GO:0050884 neuromuscular process controlling posture
GO:0050905 neuromuscular process
GO:0051965 positive regulation of synapse assembly
GO:0060079 regulation of excitatory postsynaptic membrane potential
GO:0060291 long-term synaptic potentiation
Cellular Component
GO:0000792 heterochromatin
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001739 Methyl-CpG DNA binding
IPR014756 Immunoglobulin E-set
IPR016177 DNA-binding domain
PFAM PF01429
PRINTS
PIRSF
SMART SM00391
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3N2R6
UniProt Splice Variant
Entrez Gene 539629
UniGene Bt.11246
RefSeq XP_005227752
HUGO HGNC:6990
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02070090 DAAA02070091
GenPept