Version 5.4
Bos taurus Protein: TES
Summary
InnateDB Protein IDBP-684503.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TES
Protein Name Testin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000031665
InnateDB Gene IDBG-632842 (TES)
Protein Structure
UniProt Annotation
Function Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Detected along actin stress fibers. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0030054 cell junction
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
IPR010442 PET domain
PFAM PF00412
PF06297
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2YDE9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 534965
UniGene Bt.18089
RefSeq NP_001039855
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110254 DP000008
GenPept AAI10255 ABA02560

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca