InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC38A7

Summary

InnateDB Protein

IDBP-684656.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC38A7

Protein Name

Putative sodium-coupled neutral amino acid transporter 7

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009438

InnateDB Gene

IDBG-632992 (SLC38A7)

Protein Structure

UniProt Annotation

Function

Mediates sodium-dependent transport of amino acids, preferentially L-glutamine. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=In neurons, located in soma and axons. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005290	L-histidine transmembrane transporter activity
GO:0005313	L-glutamate transmembrane transporter activity
GO:0015179	L-amino acid transmembrane transporter activity
GO:0015180	L-alanine transmembrane transporter activity
GO:0015182	L-asparagine transmembrane transporter activity
GO:0015183	L-aspartate transmembrane transporter activity
GO:0015186	L-glutamine transmembrane transporter activity
GO:0015190	L-leucine transmembrane transporter activity
GO:0015191	L-methionine transmembrane transporter activity
GO:0015194	L-serine transmembrane transporter activity

Biological Process

GO:0003333	amino acid transmembrane transport
GO:0006810	transport
GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0006865	amino acid transport
GO:0006867	asparagine transport
GO:0006868	glutamine transport
GO:0015803	branched-chain amino acid transport
GO:0015804	neutral amino acid transport
GO:0015807	L-amino acid transport
GO:0015808	L-alanine transport
GO:0015810	aspartate transport
GO:0015813	L-glutamate transport
GO:0015817	histidine transport
GO:0015821	methionine transport
GO:0015825	L-serine transport
GO:1902475	L-alpha-amino acid transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR013057 Amino acid transporter, transmembrane
IPR018227 Tryptophan/tyrosine permease

PFAM

PF01490
PF03222

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A7E3U5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

513110

UniGene

Bt.53312

RefSeq

NP_001093825

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BT030716

GenPept

ABS45032