InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FARP1

Summary

InnateDB Protein

IDBP-684763.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FARP1

Protein Name

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000167

InnateDB Gene

IDBG-633077 (FARP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0032321	positive regulation of Rho GTPase activity
GO:0035023	regulation of Rho protein signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0019898	extrinsic component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000219 Dbl homology (DH) domain
IPR000299 FERM domain
IPR000798 Ezrin/radixin/moesin like
IPR001849 Pleckstrin homology domain
IPR014847 FERM adjacent (FA)
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain

PFAM

PF00621
PF00169
PF08736
PF09379
PF09380
PF00373

PRINTS

PR00661
PR00935

PIRSF

SMART

SM00325
SM00233
SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt