InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SETDB1

Summary

InnateDB Protein

IDBP-685017.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SETDB1

Protein Name

SET domain, bifurcated 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000107

InnateDB Gene

IDBG-633289 (SETDB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 114 interaction(s) predicted by orthology.

Predicted by orthology
Total	114 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0008270	zinc ion binding
GO:0016740	transferase activity
GO:0018024	histone-lysine N-methyltransferase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001833	inner cell mass cell proliferation
GO:0032259	methylation
GO:0034968	histone lysine methylation
GO:0036124	histone H3-K9 trimethylation
GO:0060348	bone development

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001214 SET domain
IPR001739 Methyl-CpG DNA binding
IPR002999 Tudor domain
IPR003606 Pre-SET zinc-binding sub-group
IPR003616 Post-SET domain
IPR007728 Pre-SET domain
IPR016177 DNA-binding domain
IPR016197 Chromo domain-like

PFAM

PF00856
PF01429
PF00567
PF05033

PRINTS

PIRSF

SMART

SM00317
SM00391
SM00333
SM00468
SM00508

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite