Version 5.4
Bos taurus Protein: WSB2
Summary
InnateDB Protein IDBP-685194.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WSB2
Protein Name WD repeat and SOCS box-containing protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009395
InnateDB Gene IDBG-633480 (WSB2)
Protein Structure
UniProt Annotation
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001496 SOCS protein, C-terminal
IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF07525
PF00400
PRINTS PR00320
PIRSF
SMART SM00253
SM00969
SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0V8J1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 508388
UniGene Bt.109198
RefSeq NP_001068825
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT026227
GenPept ABG67066

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca