Version 5.4
Bos taurus Protein: BT.54393
Summary
InnateDB Protein IDBP-685241.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.54393
Protein Name high affinity immunoglobulin gamma Fc receptor I
Synonyms CD64; FCGR1; FCGR1B;
Species Bos taurus
Ensembl Protein ENSBTAP00000011333
InnateDB Gene IDBG-633524 (BT.54393)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019770 IgG receptor activity
GO:0019864 IgG binding
Biological Process
GO:0001788 antibody-dependent cellular cytotoxicity
GO:0001798 positive regulation of type IIa hypersensitivity
GO:0001805 positive regulation of type III hypersensitivity
GO:0006898 receptor-mediated endocytosis
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0007166 cell surface receptor signaling pathway
GO:0009617 response to bacterium
GO:0019884 antigen processing and presentation of exogenous antigen
GO:0038094 Fc-gamma receptor signaling pathway
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042742 defense response to bacterium
GO:0050766 positive regulation of phagocytosis
GO:0050776 regulation of immune response
Cellular Component
GO:0009897 external side of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013151 Immunoglobulin
PFAM PF00047
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9MZT0
UniProt Splice Variant
Entrez Gene 282227
UniGene Bt.54393
RefSeq NP_776963
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF162866 DAAA02007276
GenPept AAF80477

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca