Version 5.4
Bos taurus Protein: HNRNPA2B1
Summary
InnateDB Protein IDBP-685340.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNRNPA2B1
Protein Name Heterogeneous nuclear ribonucleoproteins A2/B1
Synonyms HNRPA2B1;
Species Bos taurus
Ensembl Protein ENSBTAP00000007527
InnateDB Gene IDBG-633624 (HNRNPA2B1)
Protein Structure
UniProt Annotation
Function Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, but also found in the cytoplasm of cells in some tissues. Not found in the nucleolus (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.
Predicted by orthology
Total 84 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR021662 Nuclear factor hnRNPA1
PFAM PF00076
PF11627
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2HJ60
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 507564
UniGene Bt.48137
RefSeq NP_001039440
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113298
GenPept AAI13299

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca