InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GNE

Summary

InnateDB Protein

IDBP-685379.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNE

Protein Name

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001520

InnateDB Gene

IDBG-633656 (GNE)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005524	ATP binding
GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity
GO:0009384	N-acylmannosamine kinase activity
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006047	UDP-N-acetylglucosamine metabolic process
GO:0009103	lipopolysaccharide biosynthetic process
GO:0046380	N-acetylneuraminate biosynthetic process
GO:0046835	carbohydrate phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000600 ROK
IPR001312 Hexokinase
IPR003331 UDP-N-acetylglucosamine 2-epimerase
IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing

PFAM

PF00480
PF02350

PRINTS

PR00475

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02023137

GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca