Version 5.4
Bos taurus Protein: C2
Summary
InnateDB Protein IDBP-685427.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C2
Protein Name complement C2 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000042824
InnateDB Gene IDBG-633680 (C2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006956 complement activation
GO:2000427 positive regulation of apoptotic cell clearance
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000436 Sushi/SCR/CCP
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR002035 von Willebrand factor, type A
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR011360 Complement B/C2
PFAM PF00084
PF00089
PF00092
PRINTS PR00722
PIRSF PIRSF001154
SMART SM00032
SM00020
SM00327
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0V7N2
UniProt Splice Variant
Entrez Gene 515440
UniGene Bt.48846
RefSeq XP_005223711
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT026538 DAAA02055371
GenPept ABH06325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca