Version 5.4
Bos taurus Protein: TBX3
Summary
InnateDB Protein IDBP-685460.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBX3
Protein Name T-box 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028930
InnateDB Gene IDBG-633724 (TBX3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001085 RNA polymerase II transcription factor binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001501 skeletal system development
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001947 heart looping
GO:0003007 heart morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003167 atrioventricular bundle cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007569 cell aging
GO:0008284 positive regulation of cell proliferation
GO:0008595 anterior/posterior axis specification, embryo
GO:0009887 organ morphogenesis
GO:0010159 specification of organ position
GO:0019827 stem cell maintenance
GO:0021761 limbic system development
GO:0030539 male genitalia development
GO:0030540 female genitalia development
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030879 mammary gland development
GO:0032275 luteinizing hormone secretion
GO:0035108 limb morphogenesis
GO:0035115 embryonic forelimb morphogenesis
GO:0035136 forelimb morphogenesis
GO:0042127 regulation of cell proliferation
GO:0042733 embryonic digit morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0045662 negative regulation of myoblast differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046884 follicle-stimulating hormone secretion
GO:0048332 mesoderm morphogenesis
GO:0055007 cardiac muscle cell differentiation
GO:0060021 palate development
GO:0060412 ventricular septum morphogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060596 mammary placode formation
GO:0060923 cardiac muscle cell fate commitment
GO:0060931 sinoatrial node cell development
GO:0090398 cellular senescence
GO:2000648 positive regulation of stem cell proliferation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR002070 Transcription factor, Brachyury
IPR008967 p53-like transcription factor, DNA-binding
IPR022582 Transcription factor, T-box, region of unknown function
PFAM PF00907
PF12598
PRINTS PR00937
PR00938
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BK57
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:11602
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045388 DAAA02045389
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca