InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FYTTD1

Summary

InnateDB Protein

IDBP-685474.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FYTTD1

Protein Name

UAP56-interacting factor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043895

InnateDB Gene

IDBG-633740 (FYTTD1)

Protein Structure

UniProt Annotation

Function

Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4 (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006406	mRNA export from nucleus
GO:0006810	transport
GO:0051028	mRNA transport

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0016607	nuclear speck

Protein Structure and Domains

PDB ID

InterPro

IPR009782 Protein of unknown function DUF1346

PFAM

PF07078

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q17QU6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

407149

UniGene

RefSeq

NP_001001137

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AJ344095 BC118174

GenPept

AAI18175 CAC51428