InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LYZ

Summary

InnateDB Protein

IDBP-685802.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LYZ

Protein Name

Lysozyme C, non-stomach isozyme

Synonyms

LYS; LZ;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000038081

InnateDB Gene

IDBG-634051 (LYZ)

Protein Structure

UniProt Annotation

Function

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in blood cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003796	lysozyme activity
GO:0003824	catalytic activity
GO:0016787	hydrolase activity
GO:0016798	hydrolase activity, acting on glycosyl bonds

Biological Process

GO:0008152	metabolic process
GO:0016998	cell wall macromolecule catabolic process
GO:0019835	cytolysis
GO:0042742	defense response to bacterium

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000974 Glycoside hydrolase, family 22, lysozyme
IPR001916 Glycoside hydrolase, family 22
IPR008258 Lytic transglycosylase-like SLT domain
IPR023346 Lysozyme-like domain

PFAM

PF00062
PF01464
PF13406

PRINTS

PR00137
PR00135

PIRSF

SMART

SM00263

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt