InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TPCN1

Summary

InnateDB Protein

IDBP-685852.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TPCN1

Protein Name

two pore segment channel 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000029529

InnateDB Gene

IDBG-634024 (TPCN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005245	voltage-gated calcium channel activity
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0072345	NAADP-sensitive calcium-release channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006816	calcium ion transport
GO:0034220	ion transmembrane transport
GO:0034765	regulation of ion transmembrane transport
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport
GO:0086010	membrane depolarization during action potential

Cellular Component

GO:0005765	lysosomal membrane
GO:0005886	plasma membrane
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR005821 Ion transport domain

PFAM

PF00520

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MSJ0

UniProt Splice Variant

Entrez Gene

510830

UniGene

RefSeq

XP_002694563

HUGO

HGNC:18182

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02045423

GenPept