Version 5.4
Bos taurus Protein: GRM1
Summary
InnateDB Protein IDBP-685971.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRM1
Protein Name glutamate receptor, metabotropic 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000053724
InnateDB Gene IDBG-634191 (GRM1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0008066 glutamate receptor activity
Biological Process
GO:0000186 activation of MAPKK activity
GO:0000187 activation of MAPK activity
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007216 G-protein coupled glutamate receptor signaling pathway
GO:0007626 locomotory behavior
GO:0019233 sensory perception of pain
GO:0038042 dimeric G-protein coupled receptor signaling pathway
GO:0043408 regulation of MAPK cascade
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051930 regulation of sensory perception of pain
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0071257 cellular response to electrical stimulus
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0038037 G-protein coupled receptor dimeric complex
GO:0038038 G-protein coupled receptor homodimeric complex
GO:0043005 neuron projection
Protein Structure and Domains
PDB ID
InterPro IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000202 GPCR, family 3, metabotropic glutamate receptor 5
IPR000337 GPCR, family 3
IPR001256 GPCR, family 3, metabotropic glutamate receptor 1
IPR001828 Extracellular ligand-binding receptor
IPR011500 GPCR, family 3, nine cysteines domain
IPR017978 GPCR, family 3, C-terminal
IPR019588 Metabotropic glutamate receptor, Homer-binding domain
IPR028082 Periplasmic binding protein-like I
PFAM PF01094
PF07562
PF00003
PF10606
PRINTS PR00593
PR01055
PR00248
PR01051
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MDE0
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:4593
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02026952 DAAA02026953 DAAA02026954 DAAA02026955 DAAA02026956
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca