Bos taurus Protein: CHRNE | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-686007.2 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | CHRNE | ||||||||||||
Protein Name | Acetylcholine receptor subunit epsilon | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Protein | ENSBTAP00000042804 | ||||||||||||
InnateDB Gene | IDBG-634244 (CHRNE) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | ||||||||||||
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR002394
Nicotinic acetylcholine receptor IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding |
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PFAM |
PF02932
PF02931 |
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PRINTS |
PR00254
PR00252 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P02715 | ||||||||||||
PhosphoSite | PhosphoSite- | ||||||||||||
TrEMBL | Q8MI36 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 281688 | ||||||||||||
UniGene | Bt.4231 | ||||||||||||
RefSeq | NP_776697 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AB070520 AF457656 AF457657 AF457658 AF457659 X02597 | ||||||||||||
GenPept | AAN76988 BAB97296 CAA26442 | ||||||||||||