InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.61819

Summary

InnateDB Protein

IDBP-686013.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.61819

Protein Name

serine/threonine-protein kinase VRK2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045115

InnateDB Gene

IDBG-634236 (BT.61819)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0034599	cellular response to oxidative stress
GO:0043408	regulation of MAPK cascade
GO:0046777	protein autophosphorylation
GO:2000659	regulation of interleukin-1-mediated signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt