InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PPP2R5C

Summary

InnateDB Protein

IDBP-686457.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP2R5C

Protein Name

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026895

InnateDB Gene

IDBG-634666 (PPP2R5C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008601	protein phosphatase type 2A regulator activity

Biological Process

GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165	signal transduction
GO:0008285	negative regulation of cell proliferation
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0000159	protein phosphatase type 2A complex
GO:0000775	chromosome, centromeric region
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR002554 Protein phosphatase 2A, regulatory B subunit, B56
IPR016024 Armadillo-type fold

PFAM

PF01603

PRINTS

PIRSF

PIRSF028043

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A4FV55

UniProt Splice Variant

Entrez Gene

505757

UniGene

Bt.64809

RefSeq

NP_001076845

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC123756 DAAA02053275

GenPept

AAI23757