InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PAK3

Summary

InnateDB Protein

IDBP-686530.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAK3

Protein Name

p21 protein (Cdc42/Rac)-activated kinase 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013449

InnateDB Gene

IDBG-634724 (PAK3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004708	MAP kinase kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0017048	Rho GTPase binding

Biological Process

GO:0000165	MAPK cascade
GO:0000187	activation of MAPK activity
GO:0006468	protein phosphorylation
GO:0007409	axonogenesis
GO:0016310	phosphorylation
GO:0016358	dendrite development
GO:0030833	regulation of actin filament polymerization

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000095 CRIB domain
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00786
PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00285
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt