InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FAM213B

Summary

InnateDB Protein

IDBP-686552.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FAM213B

Protein Name

hypothetical protein LOC617001

Synonyms

C16H1orf93; C1orf93;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002262

InnateDB Gene

IDBG-634766 (FAM213B)

Protein Structure

UniProt Annotation

Function

Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047017	prostaglandin-F synthase activity

Biological Process

GO:0001516	prostaglandin biosynthetic process
GO:0006629	lipid metabolic process
GO:0006631	fatty acid metabolic process
GO:0006633	fatty acid biosynthetic process
GO:0006693	prostaglandin metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0043209	myelin sheath
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR012336 Thioredoxin-like fold

PFAM

PF13098
PF13192
PF13462
PF13905

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58CY6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

617001

UniGene

Bt.23076

RefSeq

NP_001035688

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC114900 BT021811

GenPept

AAI14901 AAX46658