Version 5.4
Bos taurus Protein: PIP4K2C
Summary
InnateDB Protein IDBP-686735.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIP4K2C
Protein Name Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005146
InnateDB Gene IDBG-634937 (PIP4K2C)
Protein Structure
UniProt Annotation
Function May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum. {ECO:0000250}.
Subcellular Localization Cytoplasm. Membrane. Note=Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0016310 phosphorylation
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
PFAM PF01504
PRINTS
PIRSF
SMART SM00330
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0P5F7
PhosphoSite PhosphoSite-
TrEMBL G3X6D7
UniProt Splice Variant
Entrez Gene 540005
UniGene Bt.4172
RefSeq NP_001069664
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120101 DAAA02013495
GenPept AAI20102

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca