Version 5.4
Bos taurus Protein: VIP
Summary
InnateDB Protein IDBP-686765.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VIP
Protein Name VIP peptidesIntestinal peptide PHI-27Vasoactive intestinal peptide
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000017827
InnateDB Gene IDBG-634970 (VIP)
Protein Structure
UniProt Annotation
Function VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.PHI also causes vasodilation.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
GO:0009966 regulation of signal transduction
GO:0010579 positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0032880 regulation of protein localization
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P81401
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280956
UniGene Bt.11212
RefSeq NP_776395
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF503910 BC120324
GenPept AAI20325 AAM28152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca