Version 5.4
| Bos taurus Protein: SFTPB | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-686904.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SFTPB | ||||||||
| Protein Name | Pulmonary surfactant-associated protein B | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000042549 | ||||||||
| InnateDB Gene | IDBG-635097 (SFTPB) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | ||||||||
| Subcellular Localization | Secreted, extracellular space, surface film. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR003119
Saposin type A IPR007856 Saposin-like type B, 1 IPR008138 Saposin-like type B, 2 IPR008139 Saposin B IPR008373 Saposin IPR011001 Saposin-like |
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| PFAM |
PF02199
PF05184 PF03489 |
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| PRINTS |
PR01797
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| PIRSF | |||||||||
| SMART |
SM00162
SM00741 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P15781 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 507398 | ||||||||
| UniGene | Bt.42696 | ||||||||
| RefSeq | NP_001068779 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC118395 | ||||||||
| GenPept | AAI18396 | ||||||||