InnateDB Protein
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IDBP-686950.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CINP
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Protein Name
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Cyclin-dependent kinase 2-interacting protein
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000014592
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InnateDB Gene
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IDBG-635142 (CINP)
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Protein Structure
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Function |
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR023250
Cyclin-dependent kinase 2-interacting protein
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PFAM |
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PRINTS |
PR02040
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A6H7E2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
613767
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UniGene |
Bt.29603
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RefSeq |
NP_001092595
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC146212
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GenPept |
AAI46213
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