InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: UCP2

Summary

InnateDB Protein

IDBP-687217.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UCP2

Protein Name

Mitochondrial uncoupling protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004810

InnateDB Gene

IDBG-635381 (UCP2)

Protein Structure

UniProt Annotation

Function

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006810	transport
GO:0006839	mitochondrial transport
GO:0051881	regulation of mitochondrial membrane potential

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane