Version 5.4
Bos taurus Protein: BT.37142
Summary
InnateDB Protein IDBP-687248.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.37142
Protein Name hemochromatosis
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000017371
InnateDB Gene IDBG-635416 (BT.37142)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0019882 antigen processing and presentation
GO:0042446 hormone biosynthetic process
GO:0055072 iron ion homeostasis
GO:0060586 multicellular organismal iron ion homeostasis
GO:0097459 iron ion import into cell
Cellular Component
GO:0005769 early endosome
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
GO:0042612 MHC class I protein complex
GO:0045177 apical part of cell
GO:0045178 basal part of cell
GO:0048471 perinuclear region of cytoplasm
GO:0055037 recycling endosome
Protein Structure and Domains
PDB ID
InterPro IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein
IPR027648 MHC class I alpha chain
PFAM PF00129
PF07654
PRINTS PR01638
PIRSF
SMART SM00407
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5EEZ1
UniProt Splice Variant
Entrez Gene 497622
UniGene Bt.37142
RefSeq NP_001012399
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY898807 DAAA02055498
GenPept AAW82001

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca