Version 5.4
Bos taurus Protein: PELI1
Summary
InnateDB Protein IDBP-687368.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PELI1
Protein Name protein pellino homolog 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027798
InnateDB Gene IDBG-635528 (PELI1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0001819 positive regulation of cytokine production
GO:0008063 Toll signaling pathway
GO:0030890 positive regulation of B cell proliferation
GO:0031398 positive regulation of protein ubiquitination
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032496 response to lipopolysaccharide
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
GO:0042130 negative regulation of T cell proliferation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043331 response to dsRNA
GO:0050868 negative regulation of T cell activation
GO:0050871 positive regulation of B cell activation
GO:0070936 protein K48-linked ubiquitination
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006800 Pellino family
PFAM PF04710
PRINTS
PIRSF PIRSF038886
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A0JN70
UniProt Splice Variant
Entrez Gene 535054
UniGene Bt.72254
RefSeq NP_001071472
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126542 DAAA02031421 DAAA02031422
GenPept AAI26543

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca