Version 5.4
Homo sapiens Protein: SAP30BP
Summary
InnateDB Protein IDBP-68744.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SAP30BP
Protein Name SAP30 binding protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000347592
InnateDB Gene IDBG-68742 (SAP30BP)
Protein Structure
UniProt Annotation
Function Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes. {ECO:0000250UniProtKB:Q02614, ECO:0000269PubMed:15496587}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15496587}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 49 [view]
Protein-Protein 48 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0010942 positive regulation of cell death
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR012479 SAP30-binding protein
PFAM PF07818
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHR5
PhosphoSite PhosphoSite-Q9UHR5
TrEMBL Q659G6
UniProt Splice Variant
Entrez Gene 29115
UniGene Hs.655088
RefSeq XP_005257313
HUGO HGNC:30785
OMIM 610218
CCDS
HPRD 17094
IMGT
EMBL AC087749 AF087869 AF119664 AF450482 AK002202 AK095265 AL049465 AY082382 BC007592 BC013409 BC030233 BC063793 CH471099
GenPept AAF17221 AAH07592 AAH13409 AAH30233 AAH63793 AAL47177 AAL92491 AAM10497 BAC04514 BAG51029 CAH56422 EAW89298

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca