Version 5.4
Bos taurus Protein: DCAF12
Summary
InnateDB Protein IDBP-687717.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCAF12
Protein Name DDB1- and CUL4-associated factor 12
Synonyms WDR40A;
Species Bos taurus
Ensembl Protein ENSBTAP00000028744
InnateDB Gene IDBG-635845 (DCAF12)
Protein Structure
UniProt Annotation
Function May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHH0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 525161
UniGene Bt.49830
RefSeq NP_001161368
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105241 BC150062
GenPept AAI05242 AAI50063

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca