InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TIA1

Summary

InnateDB Protein

IDBP-687808.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TIA1

Protein Name

TIA1 cytotoxic granule-associated RNA binding protein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025528

InnateDB Gene

IDBG-635927 (TIA1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0017091	AU-rich element binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0017148	negative regulation of translation
GO:0042036	negative regulation of cytokine biosynthetic process
GO:0048024	regulation of mRNA splicing, via spliceosome

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0010494	cytoplasmic stress granule
GO:0097165	nuclear stress granule

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain
IPR003954 RNA recognition motif domain, eukaryote

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360
SM00361

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q0VBZ6

UniProt Splice Variant

Entrez Gene

538533

UniGene

Bt.91654

RefSeq

NP_001069577

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC120427 DAAA02031534

GenPept

AAI20428