Version 5.4
Bos taurus Protein: STX8
Summary
InnateDB Protein IDBP-687898.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX8
Protein Name Syntaxin-8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000042059
InnateDB Gene IDBG-636009 (STX8)
Protein Structure
UniProt Annotation
Function Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006906 vesicle fusion
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
PFAM PF05739
PRINTS
PIRSF
SMART SM00397
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3T075
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 613567
UniGene Bt.64576
RefSeq NP_001071505
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102537
GenPept AAI02538

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca