InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NTRK2

Summary

InnateDB Protein

IDBP-688122.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NTRK2

Protein Name

BDNF/NT-3 growth factors receptor

Synonyms

Trk-B; TrkB;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014097

InnateDB Gene

IDBG-636149 (NTRK2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005030	neurotrophin receptor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity

Biological Process

GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0038179	neurotrophin signaling pathway

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR020455 Tyrosine-protein kinase, neurotrophic receptor, type 2
IPR020777 Tyrosine-protein kinase, neurotrophic receptor

PFAM

PF01462
PF01463
PF07679

PRINTS

PR01941
PR01939

PIRSF

SMART

SM00013
SM00082
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt