Bos taurus Protein: SLC2A2 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Protein | IDBP-688305.2 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | SLC2A2 | ||||||||||||||
Protein Name | Solute carrier family 2, facilitated glucose transporter member 2 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Protein | ENSBTAP00000050612 | ||||||||||||||
InnateDB Gene | IDBG-636384 (SLC2A2) | ||||||||||||||
Protein Structure | |||||||||||||||
UniProt Annotation | |||||||||||||||
Function | Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). {ECO:0000250}. | ||||||||||||||
Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||||||||||||
Disease Associations | |||||||||||||||
Tissue Specificity | |||||||||||||||
Comments | |||||||||||||||
Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||||
PDB ID | |||||||||||||||
InterPro |
IPR002440
Glucose transporter, type 2 (GLUT2) IPR002666 Reduced folate carrier IPR003663 Sugar/inositol transporter IPR005828 General substrate transporter IPR011701 Major facilitator superfamily IPR016196 Major facilitator superfamily domain, general substrate transporter IPR020846 Major facilitator superfamily domain |
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PFAM |
PF01770
PF00083 PF07690 |
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PRINTS |
PR01191
PR00171 |
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PIRSF |
PIRSF028739
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SMART | |||||||||||||||
TIGRFAMs | |||||||||||||||
Post-translational Modifications | |||||||||||||||
Modification | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | P58351 | ||||||||||||||
PhosphoSite | PhosphoSite- | ||||||||||||||
TrEMBL | A5HNF0 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 282357 | ||||||||||||||
UniGene | Bt.13076 | ||||||||||||||
RefSeq | NP_001096692 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | AF308828 BC149324 EF544428 | ||||||||||||||
GenPept | AAI49325 AAK63201 ABQ12422 | ||||||||||||||