Version 5.4
Bos taurus Protein: TOR1AIP1
Summary
InnateDB Protein IDBP-688815.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOR1AIP1
Protein Name torsin-1A-interacting protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000033870
InnateDB Gene IDBG-636822 (TOR1AIP1)
Protein Structure
UniProt Annotation
Function Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001671 ATPase activator activity
GO:0005515 protein binding
Biological Process
GO:0032781 positive regulation of ATPase activity
GO:0034504 protein localization to nucleus
GO:0071763 nuclear membrane organization
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008662 Lamina-associated polypeptide 1C
PFAM PF05609
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt F1N4E5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 782528
UniGene Bt.89545
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043477
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca