Version 5.4
Bos taurus Protein: WAS
Summary
InnateDB Protein IDBP-688840.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WAS
Protein Name Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000056444
InnateDB Gene IDBG-636860 (WAS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 72 interaction(s) predicted by orthology.
Predicted by orthology
Total 72 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006955 immune response
GO:0007015 actin filament organization
GO:0008154 actin polymerization or depolymerization
GO:0016197 endosomal transport
GO:0030041 actin filament polymerization
GO:0030048 actin filament-based movement
GO:0042110 T cell activation
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
GO:0005911 cell-cell junction
GO:0012506 vesicle membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000095 CRIB domain
IPR000697 WH1/EVH1
IPR011026 Wiscott-Aldrich syndrome protein, C-terminal
PFAM PF00786
PF00568
PRINTS
PIRSF
SMART SM00285
SM00461
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3N3E1
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:12731
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02073063 DAAA02073064 DAAA02073065 DAAA02073066
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca