InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ROR2

Summary

InnateDB Protein

IDBP-688984.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ROR2

Protein Name

receptor tyrosine kinase-like orphan receptor 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053765

InnateDB Gene

IDBG-637006 (ROR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005109	frizzled binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0017147	Wnt-protein binding

Biological Process

GO:0001501	skeletal system development
GO:0001502	cartilage condensation
GO:0001756	somitogenesis
GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway
GO:0007254	JNK cascade
GO:0008285	negative regulation of cell proliferation
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0030154	cell differentiation
GO:0030335	positive regulation of cell migration
GO:0030538	embryonic genitalia morphogenesis
GO:0042472	inner ear morphogenesis
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060071	Wnt signaling pathway, planar cell polarity pathway
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000001 Kringle
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR011009 Protein kinase-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013806 Kringle-like fold
IPR016247 Tyrosine-protein kinase, receptor ROR
IPR020067 Frizzled domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM