Version 5.4
Bos taurus Protein: CHPT1
Summary
InnateDB Protein IDBP-689074.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHPT1
Protein Name Cholinephosphotransferase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003236
InnateDB Gene IDBG-637087 (CHPT1)
Protein Structure
UniProt Annotation
Function Catalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004142 diacylglycerol cholinephosphotransferase activity
GO:0016740 transferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006657 CDP-choline pathway
GO:0006663 platelet activating factor biosynthetic process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000462 CDP-alcohol phosphatidyltransferase
IPR014472 Choline/ethanolamine phosphotransferase
PFAM PF01066
PRINTS
PIRSF PIRSF015665
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1LZE6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 511291
UniGene Bt.104675
RefSeq NP_001068975
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116046
GenPept AAI16047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca