InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DHX9

Summary

InnateDB Protein

IDBP-689081.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DHX9

Protein Name

ATP-dependent RNA helicase A

Synonyms

DDX9; RHA;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026409

InnateDB Gene

IDBG-637077 (DHX9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 144 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	144 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0001085	RNA polymerase II transcription factor binding
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0006200	ATP catabolic process
GO:0007623	circadian rhythm
GO:0008152	metabolic process
GO:0034605	cellular response to heat
GO:0070934	CRD-mediated mRNA stabilization

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005813	centrosome
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex
GO:0036464	cytoplasmic ribonucleoprotein granule
GO:0070937	CRD-mediated mRNA stability complex

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR007502 Helicase-associated domain
IPR011545 DEAD/DEAH box helicase domain
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014720 Double-stranded RNA-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04408
PF00270
PF07717
PF00035

PRINTS

PIRSF

SMART

SM00490
SM00847
SM00487
SM00358

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite