Version 5.4
Bos taurus Protein: DDT
Summary
InnateDB Protein IDBP-689110.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDT
Protein Name D-dopachrome decarboxylase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029458
InnateDB Gene IDBG-637127 (DDT)
Protein Structure
UniProt Annotation
Function Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016829 lyase activity
GO:0033981 D-dopachrome decarboxylase activity
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001398 Macrophage migration inhibitory factor
IPR014347 Tautomerase/MIF superfamily
PFAM PF01187
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A5PK65
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 615999
UniGene
RefSeq NP_001092620
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142376
GenPept AAI42377

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca