InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SGMS1

Summary

InnateDB Protein

IDBP-689186.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SGMS1

Protein Name

sphingomyelin synthase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015599

InnateDB Gene

IDBG-637178 (SGMS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0033188	sphingomyelin synthase activity
GO:0047493	ceramide cholinephosphotransferase activity

Biological Process

GO:0006686	sphingomyelin biosynthetic process
GO:0016049	cell growth
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0000138	Golgi trans cisterna
GO:0016020	membrane
GO:0030173	integral component of Golgi membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
IPR001660 Sterile alpha motif domain
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF01569
PF00536

PRINTS

PIRSF

SMART

SM00014
SM00454

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite