Version 5.4
Bos taurus Protein: ERP70
Summary
InnateDB Protein IDBP-689189.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERP70
Protein Name protein disulfide-isomerase A4 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022782
InnateDB Gene IDBG-637190 (ERP70)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006457 protein folding
GO:0008152 metabolic process
GO:0034976 response to endoplasmic reticulum stress
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0009986 cell surface
Protein Structure and Domains
PDB ID
InterPro IPR001393 Calsequestrin
IPR005788 Disulphide isomerase
IPR005792 Protein disulphide isomerase
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
IPR017068 Protein disulphide-isomerase A4
PFAM PF01216
PF13098
PF13192
PF13462
PF13905
PF00085
PRINTS PR00312
PIRSF PIRSF036862
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6KDN4
UniProt Splice Variant
Entrez Gene 415110
UniGene Bt.23128
RefSeq NP_001039344
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ586435 DAAA02011930
GenPept CAE52280

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca