Version 5.4
Bos taurus Protein: CYR61
Summary
InnateDB Protein IDBP-689278.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYR61
Protein Name protein CYR61
Synonyms CCN1; GIG1;
Species Bos taurus
Ensembl Protein ENSBTAP00000012977
InnateDB Gene IDBG-637282 (CYR61)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0001934 positive regulation of protein phosphorylation
GO:0002041 intussusceptive angiogenesis
GO:0003181 atrioventricular valve morphogenesis
GO:0003278 apoptotic process involved in heart morphogenesis
GO:0003281 ventricular septum development
GO:0007155 cell adhesion
GO:0010518 positive regulation of phospholipase activity
GO:0010811 positive regulation of cell-substrate adhesion
GO:0016337 single organismal cell-cell adhesion
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0030513 positive regulation of BMP signaling pathway
GO:0033690 positive regulation of osteoblast proliferation
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044319 wound healing, spreading of cells
GO:0045597 positive regulation of cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045860 positive regulation of protein kinase activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060413 atrial septum morphogenesis
GO:0060591 chondroblast differentiation
GO:0060710 chorio-allantoic fusion
GO:0060716 labyrinthine layer blood vessel development
GO:0061036 positive regulation of cartilage development
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0072593 reactive oxygen species metabolic process
GO:2000304 positive regulation of ceramide biosynthetic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR000884 Thrombospondin, type 1 repeat
IPR001007 von Willebrand factor, type C
IPR006207 Cystine knot, C-terminal
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR012395 IGFBP-related, CNN
PFAM PF00219
PF00090
PF00093
PF00007
PRINTS
PIRSF PIRSF036495
SMART SM00121
SM00209
SM00214
SM00041
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3ZC35
UniProt Splice Variant
Entrez Gene 508941
UniGene Bt.49598
RefSeq NP_001029512
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102934 DAAA02008068
GenPept AAI02935

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca