InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BCL10

Summary

InnateDB Protein

IDBP-689284.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BCL10

Protein Name

B-cell lymphoma/leukemia 10

Synonyms

CARMEN; CIPER;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018398

InnateDB Gene

IDBG-637289 (BCL10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.

Predicted by orthology
Total	52 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008134	transcription factor binding
GO:0019209	kinase activator activity
GO:0019899	enzyme binding
GO:0019900	kinase binding
GO:0019901	protein kinase binding
GO:0031625	ubiquitin protein ligase binding
GO:0043130	ubiquitin binding
GO:0043422	protein kinase B binding
GO:0043621	protein self-association
GO:0051059	NF-kappaB binding

Biological Process

GO:0001783	B cell apoptotic process
GO:0001843	neural tube closure
GO:0002237	response to molecule of bacterial origin
GO:0002906	negative regulation of mature B cell apoptotic process
GO:0006968	cellular defense response
GO:0008219	cell death
GO:0009620	response to fungus
GO:0016064	immunoglobulin mediated immune response
GO:0031398	positive regulation of protein ubiquitination
GO:0032094	response to food
GO:0042327	positive regulation of phosphorylation
GO:0042981	regulation of apoptotic process
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087	innate immune response
GO:0045416	positive regulation of interleukin-8 biosynthetic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0050852	T cell receptor signaling pathway
GO:0050856	regulation of T cell receptor signaling pathway
GO:0050870	positive regulation of T cell activation
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051259	protein oligomerization
GO:0051260	protein homooligomerization
GO:0070231	T cell apoptotic process
GO:0071260	cellular response to mechanical stimulus
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0001772	immunological synapse
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005829	cytosol
GO:0005881	cytoplasmic microtubule
GO:0032449	CBM complex
GO:0042101	T cell receptor complex
GO:0043234	protein complex
GO:0045121	membrane raft
GO:0046696	lipopolysaccharide receptor complex
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001315 CARD domain
IPR011029 Death-like domain

PFAM

PF00619

PRINTS

PIRSF

SMART

SM00114

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q17QJ6

UniProt Splice Variant

Entrez Gene

540824

UniGene

Bt.67501

RefSeq

NP_001071496

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC118326 DAAA02008072 DAAA02008073 JN195812

GenPept

AAI18327 AEQ33592