Bos taurus Protein: ARHGEF9
Summary
InnateDB Protein IDBP-689776.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF9
Protein Name Rho guanine nucleotide exchange factor 9
Synonyms ARHGEF9;
Species Bos taurus
Ensembl Protein ENSBTAP00000016923
InnateDB Gene IDBG-637749 (ARHGEF9)
Protein Structure
UniProt Annotation
Function Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR011511 Variant SH3 domain
PFAM PF00621
PF00018
PF14604
PF00169
PF07653
PRINTS PR00452
PIRSF
SMART SM00325
SM00326
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q58DL7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 537718
UniGene Bt.30427
RefSeq NP_001030495
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021580
GenPept AAX46427