Version 5.4
Bos taurus Protein: MYCN
Summary
InnateDB Protein IDBP-689814.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYCN
Protein Name v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000031763
InnateDB Gene IDBG-637789 (MYCN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001502 cartilage condensation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0010942 positive regulation of cell death
GO:0030324 lung development
GO:0042733 embryonic digit morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048704 embryonic skeletal system morphogenesis
GO:0048712 negative regulation of astrocyte differentiation
GO:0048754 branching morphogenesis of an epithelial tube
GO:2000378 negative regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002418 Transcription regulator Myc
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR012682 Transcription regulator Myc, N-terminal
PFAM PF00010
PF01056
PRINTS PR00044
PIRSF PIRSF001705
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MS90
UniProt Splice Variant
Entrez Gene 616888
UniGene
RefSeq XP_002691569
HUGO HGNC:7559
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031831
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca