InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MYH9

Summary

InnateDB Protein

IDBP-690077.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYH9

Protein Name

myosin, heavy chain 9, non-muscle

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013737

InnateDB Gene

IDBG-638003 (MYH9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 97 interaction(s) predicted by orthology.

Predicted by orthology
Total	97 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000146	microfilament motor activity
GO:0000166	nucleotide binding
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0030898	actin-dependent ATPase activity
GO:0042803	protein homodimerization activity
GO:0043495	protein anchor
GO:0043531	ADP binding
GO:0044822	poly(A) RNA binding
GO:0051015	actin filament binding

Biological Process

GO:0000212	meiotic spindle organization
GO:0000904	cell morphogenesis involved in differentiation
GO:0000910	cytokinesis
GO:0001525	angiogenesis
GO:0001701	in utero embryonic development
GO:0001768	establishment of T cell polarity
GO:0006200	ATP catabolic process
GO:0006509	membrane protein ectodomain proteolysis
GO:0006928	cellular component movement
GO:0007155	cell adhesion
GO:0007520	myoblast fusion
GO:0008360	regulation of cell shape
GO:0015031	protein transport
GO:0016337	single organismal cell-cell adhesion
GO:0030048	actin filament-based movement
GO:0030220	platelet formation
GO:0030224	monocyte differentiation
GO:0031032	actomyosin structure organization
GO:0031532	actin cytoskeleton reorganization
GO:0032796	uropod organization
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043534	blood vessel endothelial cell migration
GO:0051295	establishment of meiotic spindle localization

Cellular Component

GO:0001725	stress fiber
GO:0001726	ruffle
GO:0001772	immunological synapse
GO:0001931	uropod
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005819	spindle
GO:0005826	actomyosin contractile ring
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005913	cell-cell adherens junction
GO:0005938	cell cortex
GO:0008180	COP9 signalosome
GO:0008305	integrin complex
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0016459	myosin complex
GO:0016460	myosin II complex
GO:0030863	cortical cytoskeleton
GO:0031252	cell leading edge
GO:0031594	neuromuscular junction
GO:0032154	cleavage furrow
GO:0042641	actomyosin
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome
GO:0097513	myosin II filament

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR002928 Myosin tail
IPR004009 Myosin, N-terminal, SH3-like
IPR008989 Myosin S1 fragment, N-terminal
IPR009053 Prefoldin
IPR016137 Regulator of G protein signalling superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF01576
PF02736

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00242
SM00315

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt